{"id":5321,"date":"2026-10-13T20:57:59","date_gmt":"2026-10-13T20:57:59","guid":{"rendered":"https:\/\/rhf.dev01.usco.ca\/?post_type=rhf-ingenious&#038;p=5321"},"modified":"2026-10-13T20:57:59","modified_gmt":"2026-10-13T20:57:59","slug":"les-effets-de-lurocortine-2-sur-la-polarisation-de-la-microglie-m1-lexpression-genique-du-cmh-de-classe-ii-et-le-stress-oxydant","status":"publish","type":"rhf-ingenious","link":"https:\/\/rhf.dev01.usco.ca\/fr\/ingenious-projects\/les-effets-de-lurocortine-2-sur-la-polarisation-de-la-microglie-m1-lexpression-genique-du-cmh-de-classe-ii-et-le-stress-oxydant\/","title":{"rendered":"Les effets de l\u2019urocortine\u00a02 sur la polarisation de la microglie\u00a0M1, l\u2019expression g\u00e9nique du CMH de classe\u00a0II et le stress oxydant"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"5321\" class=\"elementor elementor-5321 elementor-4499\" data-elementor-post-type=\"rhf-ingenious\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e2c15c1 e-con-full rhf-story-hero e-flex e-con e-parent\" data-id=\"e2c15c1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6e8518b elementor-widget elementor-widget-heading\" data-id=\"6e8518b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Les effets de l\u2019urocortine\u00a02 sur la polarisation de la microglie\u00a0M1, l\u2019expression g\u00e9nique du CMH de classe\u00a0II et le stress oxydant<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2a95c13 e-con-full rhf-story-body e-flex e-con e-parent\" data-id=\"2a95c13\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7fa7d77 elementor-widget elementor-widget-html\" data-id=\"7fa7d77\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div class=\"rhf-story-chips\"><span>Ingenious+<\/span><span>Sant\u00e9 et bien-\u00eatre<\/span><span>BC<\/span><span>2026<\/span><span>2026<\/span><span>Laur\u00e9at r\u00e9gional<\/span><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b1f3886 elementor-widget elementor-widget-heading\" data-id=\"b1f3886\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Projet pr\u00e9sent\u00e9 par : Andre Yao et Lucas Chen <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-855f01b elementor-widget elementor-widget-text-editor\" data-id=\"855f01b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>R\u00e9gion : Vancouver (Colombie-Britannique)<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-46485bf elementor-widget elementor-widget-image\" data-id=\"46485bf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"690\" height=\"524\" src=\"https:\/\/rhf.dev01.usco.ca\/wp-content\/uploads\/2026\/10\/Lowers-TNF-\u03b1-production-1.png\" class=\"attachment-full size-full wp-image-3537\" alt=\"\" srcset=\"https:\/\/rhf.dev01.usco.ca\/wp-content\/uploads\/2026\/10\/Lowers-TNF-\u03b1-production-1.png 690w, https:\/\/rhf.dev01.usco.ca\/wp-content\/uploads\/2026\/10\/Lowers-TNF-\u03b1-production-1-300x228.png 300w\" sizes=\"(max-width: 690px) 100vw, 690px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\"><\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bc0bb5c elementor-widget elementor-widget-heading\" data-id=\"bc0bb5c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Description du projet<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-532cb8e elementor-widget elementor-widget-text-editor\" data-id=\"532cb8e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Cette innovation th\u00e9rapeutique porte sur la fa\u00e7on dont l\u2019urocortine\u00a02 aide \u00e0 att\u00e9nuer l\u2019inflammation nocive du cerveau en dirigeant des cellules immunitaires vers les points de gu\u00e9rison apr\u00e8s un accident vasculaire c\u00e9r\u00e9bral h\u00e9morragique.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-448853a elementor-widget elementor-widget-button\" data-id=\"448853a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/rhf.dev01.usco.ca\/fr\/projets-ingenious\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Voir tous les projets<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ccce9f5 elementor-widget elementor-widget-template\" data-id=\"ccce9f5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"template.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-template\">\n\t\t\t\t\t<div data-elementor-type=\"container\" data-elementor-id=\"3302\" class=\"elementor elementor-3302 elementor-bc-flex-widget\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1bccb40 e-con-full rhf-shared-newsletter e-flex e-con e-child\" data-id=\"1bccb40\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-0a65795 e-con-full subscribe-top e-flex e-con e-child\" data-id=\"0a65795\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-9f93a63 e-con-full subscribe-copy e-flex e-con e-child\" data-id=\"9f93a63\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8ee284e elementor-widget elementor-widget-heading\" data-id=\"8ee284e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Abonnez-vous \u00e0 notre infolettre<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-nlsub24 rhf-newsletter-subtitle elementor-widget elementor-widget-heading\" data-id=\"nlsub24\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Un potentiel partag\u00e9 dans votre bo\u00eete de r\u00e9ception<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-709294d elementor-widget elementor-widget-text-editor\" data-id=\"709294d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Abonnez-vous \u00e0 notre infolettre mensuelle pour d\u00e9couvrir les derni\u00e8res nouvelles, histoires, occasions et mises \u00e0 jour de nos programmes et initiatives.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9bd4774 nl-signup-archive elementor-widget elementor-widget-button\" data-id=\"9bd4774\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm rhf-newsletter-text-link\" href=\"https:\/\/rhf.dev01.usco.ca\/fr\/infolettres\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Lire l\u2019infolettre de la FRH<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-09312f5 rhf-newsletter-form elementor-button-align-stretch elementor-widget elementor-widget-form\" data-id=\"09312f5\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;button_width&quot;:&quot;100&quot;,&quot;step_next_label&quot;:&quot;Next&quot;,&quot;step_previous_label&quot;:&quot;Previous&quot;,&quot;step_type&quot;:&quot;number_text&quot;,&quot;step_icon_shape&quot;:&quot;circle&quot;}\" data-widget_type=\"form.default\">\n\t\t\t\t\t\t\t<form class=\"elementor-form\" method=\"post\" name=\"RHF Newsletter FR\" aria-label=\"RHF Newsletter FR\">\n\t\t\t<input type=\"hidden\" name=\"post_id\" value=\"3302\"\/>\n\t\t\t<input type=\"hidden\" name=\"form_id\" value=\"09312f5\"\/>\n\t\t\t<input type=\"hidden\" name=\"referer_title\" value=\"RideauHall\" \/>\n\n\t\t\t\n\t\t\t<div class=\"elementor-form-fields-wrapper elementor-labels-above\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-email elementor-field-group elementor-column elementor-field-group-email elementor-col-100 elementor-field-required\">\n\t\t\t\t\t\t\t\t\t\t\t\t<label for=\"form-field-email\" class=\"elementor-field-label\">\n\t\t\t\t\t\t\t\tAdresse 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value=\"qes\" id=\"form-field-interests-1\" name=\"form_fields[interests][]\"> <label for=\"form-field-interests-1\">Bourses de la reine Elizabeth II<\/label><\/span><span class=\"elementor-field-option\"><input type=\"checkbox\" value=\"sussex\" id=\"form-field-interests-2\" name=\"form_fields[interests][]\"> <label for=\"form-field-interests-2\">Restaurer le 24 Sussex<\/label><\/span><span class=\"elementor-field-option\"><input type=\"checkbox\" value=\"ajuinnata\" id=\"form-field-interests-3\" name=\"form_fields[interests][]\"> <label for=\"form-field-interests-3\">Ajuinnata<\/label><\/span><span class=\"elementor-field-option\"><input type=\"checkbox\" value=\"ggclc\" id=\"form-field-interests-4\" name=\"form_fields[interests][]\"> <label for=\"form-field-interests-4\">Conf\u00e9rence canadienne du gouverneur g\u00e9n\u00e9ral sur le leadership<\/label><\/span><span class=\"elementor-field-option\"><input type=\"checkbox\" value=\"catapult\" id=\"form-field-interests-5\" name=\"form_fields[interests][]\"> <label for=\"form-field-interests-5\">Catapulte Canada<\/label><\/span><span class=\"elementor-field-option\"><input type=\"checkbox\" value=\"cis\" id=\"form-field-interests-6\" name=\"form_fields[interests][]\"> <label for=\"form-field-interests-6\">Semaine canadienne de l\u2019innovation \/ Innovazone<\/label><\/span><span class=\"elementor-field-option\"><input type=\"checkbox\" value=\"ingenious\" id=\"form-field-interests-7\" name=\"form_fields[interests][]\"> <label for=\"form-field-interests-7\">Ing\u00e9nieux+<\/label><\/span><span class=\"elementor-field-option\"><input type=\"checkbox\" value=\"ggia\" id=\"form-field-interests-8\" name=\"form_fields[interests][]\"> <label for=\"form-field-interests-8\">Prix du gouverneur g\u00e9n\u00e9ral pour l\u2019innovation<\/label><\/span><span class=\"elementor-field-option\"><input type=\"checkbox\" value=\"forum\" id=\"form-field-interests-9\" name=\"form_fields[interests][]\"> <label 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centres d\u2019int\u00e9r\u00eat. Vous pouvez vous d\u00e9sabonner \u00e0 tout moment. <a href=\"https:\/\/rhf.dev01.usco.ca\/fr\/privacy-policy\/\">Confidentialit\u00e9<\/a>.<\/p>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-group elementor-column elementor-field-type-submit elementor-col-100 e-form__buttons\">\n\t\t\t\t\t<button class=\"elementor-button elementor-size-sm\" type=\"submit\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">S\u2019inscrire<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/button>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<input type='hidden' name='lang' value='en-us' \/><\/form>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Cette innovation th\u00e9rapeutique porte sur la fa\u00e7on dont l\u2019urocortine\u00a02 aide \u00e0 att\u00e9nuer l\u2019inflammation nocive du cerveau en dirigeant des cellules immunitaires vers les points de gu\u00e9rison apr\u00e8s un accident vasculaire c\u00e9r\u00e9bral h\u00e9morragique.<\/p>\n","protected":false},"featured_media":3537,"template":"elementor_header_footer","meta":{"_acf_changed":false},"rhf-ip-year":[231],"rhf-ip-region":[211],"rhf-ip-category":[233],"class_list":["post-5321","rhf-ingenious","type-rhf-ingenious","status-publish","has-post-thumbnail","hentry","rhf-ip-year-2026-2","rhf-ip-region-bc","rhf-ip-category-sante"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - 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